22MAR

Nexte issue of the journal ICAMOP

The next issue of the journal ICAMOP will be published by January 20, 2021. Submit your articles by email to: rabatuniv@gmail.com
The next issue will deal with issues related to engineering studies and system design.

ICAMOP journal
http://www.icamop.periodikos.com.br/article/5ca143cb0e8825c7409ed45d
ICAMOP journal
Review

Evaluation of R&D investment projects for a new pharmaceutical product

Rhita NEHHAS, Abdelmajid ELOUADI, M. Taib BELGHITI

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Abstract

The decision to invest in an uncertain situation is by definition risky. It often leads the decision-maker to buy additional information to limit the risk of wrong conclusions. But is it still a good solution? The objective of this state of the art synthesis is to present the different models for evaluating development strategies in situations of uncertainty in order to confirm the interest of carrying out a preliminary study to obtain new information. The models with the alternatives are all based on Monte Carlo method.

Keywords

risk management, decision, uncertainty, Monte Carlo simulation, R&D project, investment strategy, choice

References

[1]    M. Keynes, General Theory of Employment, Interest, Money, 1936, quoted by A. Galesne, Choice of investments in the company, Cerefia, October 1996.
[2]    Schwartz L., Vertinsky I., Multi-attribute investment decisions: a study of R&D project selection, Management Science, 24:3, 1977, pp. 285-301.
[3]    Costello D., A practical approach to R&D project selection, Technological forecasting and social change, 23, pp. 353-368, 1983.
[4]    Danila N., Strategic evaluation and selection of R&D projects, R&D Management, 19:1, pp. 47-62, 1989.
[5]    Di Masi J., R&D efficiency savings viewed by tufts, Market letter, September 23, 2002.
[6]    Gourc, D., Bougaret S., Lacoste G., The management of uncertainty in new product design projects: an original approach based on threat/opportunity speculation, International Review of Project Management and Management, Vol III, n° 2, 2001, ISSN 1192-9480.
[7]    M. Santi, Risk analysis of a business plan, booklet "The art of risk management" in Les Echos, Vol 3, 2000.
[8]    GOURC, Didier, BOUGARET, Sophie, and LACOSTE, Germain. Evaluation of new product development strategies in uncertain situations. Case of a pharmaceutical R&D project. European Journal of Automated Systems (JESA), 2004, vol. 38, no. 7-8, pp. 847-872.
[9]    Zopounidis C., Multicriteria decision aid in financial management, European Journal of Operational Research, 119, 1999, pp. 404-415.
[10]    Lutz, F., The theory of investment of the firm, Princeton University Press, 1951.
[11]    Hertz D.B., Risk in capital investment, Harvard Business Review, pp. 95-106, 1964.
[12]    Jacob, W.F. and Kwak Y.H.,. In search of innovative techniques to evaluate pharmaceutical R&D projects. Technovation, 23, 2003, pp. 291-296.
[13]    Doctor R.N., Newton D.P., Pearson A., Managing uncertainty in research and development, Technovation, 21, pp. 79-90, 2001.
[14]    Ghasemzadeh F., Archer N.P., Project portfolio selection through decision support, Decision Support Systems, 29, pp. 73-88, 2000.
[15]    GOURC, Didier, BOUGARET, Sophie, and BURTIN, Bernard. A model for evaluating the profitability of uncertain projects using Monte Carlo simulation: application to a drug project. In: QUALITA 2005-6th International Multidisciplinary Congress on Quality and Operational Safety. 2005. p. 9 p.
[16]    von Neumann, John, Various Techniques Used in Connection with Random Digits, U.S. Department of Commerce, National Bureau of Standards, Applied Mathematics Series 12, 1951;
[17]    PLATON, Victor et CONSTANTINESCU, Andreea. Monte Carlo Method in risk analysis for investment projects. Procedia Economics and Finance, 2014, vol. 15, p. 393-400.
 

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